The relationship between fat attenuation index of pericoronary adipose tissue and coro-nary slow flow
10.20039/j.cnki.1007-3949.2025.10.005
- VernacularTitle:冠状动脉周围脂肪组织脂肪衰减指数与冠状动脉慢血流的关系
- Author:
Aixia LIANG
1
;
Jingwu WANG
1
;
Min XU
1
;
Qian WANG
1
;
Kelu SUN
1
Author Information
1. 中国人民解放军联勤保障部队第九〇一医院心血管内科,安徽省 合肥市 230031
- Publication Type:Journal Article
- Keywords:
pericoronary adipose tissue;
fat attenuation index;
coronary slow flow;
coronary heart disease
- From:
Chinese Journal of Arteriosclerosis
2025;33(10):864-869
- CountryChina
- Language:Chinese
-
Abstract:
Aim To investigate the relationship between fat attenuation index(FAI)of pericoronary adipose tis-sue and coronary slow flow(CSF).Methods The clinical data of 135 hospitalized patients who underwent coronary angiography(CAG)due to chest tightness,chest pain and other similar symptoms from November 2023 to July 2024 were retrospectively collected.According to the blood flow grading criteria,the patients were divided into CSF group(n=61)and normal blood flow group(n=74).The basic information of the patients,the laboratory test results on the day of ad-mission and the data of coronary CT angiography(CCTA)were also collected.Multivariate Logistic regression was used to analyze the risk factors for CSF.The receiver operating characteristic(ROC)curve was used to evaluate the efficacy of FAI in predicting CSF.Results The white blood cell count(WBC),fasting blood glucose(FBG),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)and right coronary artery(RCA)FAI in the CSF group were 1.23,1.10,1.33 1.53 and 1.13 times that of those in the normal blood flow group,respectively(P＜0.05).The left ventricu-lar ejection fraction(LVEF)in the CSF group was 94.78％of the normal blood flow group(P＜0.05).Multivariate Lo-gistic regression analysis showed that elevated WBC(OR=1.891),elevated FBG(OR=1.774),decreased LVEF(OR=0.094),elevated hs-CRP increased(OR=1.124),increased RCA-FAI(OR=1.077)were independent risk factors for CSF(P＜0.05).The results of ROC curve analysis showed that the area under the curve(AUC)of RCA-FAI in predic-ting CSF was 0.715(95％CI:0.627～0.802),the optimal cut-off value was-81.5 HU,the sensitivity was 0.803,and the specificity was 0.581.Conclusion Elevated WBC,elevated FBG,decreased LVEF,increased hs-CRP,and in-creased RCA-FAI are risk factors for CSF.Among them,RCA-FAI has a good efficacy in predicting the occurrence of CSF,which can be used to identify high-risk CSF patients as early as possible and reduce the incidence of CSF.
