Diagnosis and Treatment of a Case of Spironolactone-Associated Asymptomatic Hyperuricemia After Renal Transplantation
10.3870/j.issn.1004-0781.2025.10.006
- VernacularTitle:1例肾移植术后螺内酯相关性无症状高尿酸血症的诊断与治疗
- Author:
Yun XIAO
1
;
Xiaoyu HAN
;
Chao ZHENG
;
Yu FU
;
Hanbin XIONG
;
Bin ZOU
;
Baolin WANG
;
Hua ZOU
;
Chenglong YIN
;
Zhengyao JIANG
;
Sheng ZOU
;
Anle DU
;
Guohui LI
;
Xiaohui GUO
;
Lin ZHONG
;
Jiake HE
Author Information
1. 南昌大学第二附属医院药学部,南昌 330006;南昌大学临床药理研究所,南昌 330031;南昌大学药学院,南昌 330006
- Publication Type:Journal Article
- Keywords:
Spironolactone;
Renal transplantation;
Hyperuricemia;
Individualized medicine
- From:
Herald of Medicine
2025;44(10):1562-1565
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the identification method,pathogenesis,clinical characteristics and individualized pharmacotherapy of asymptomatic hyperuricemia after renal transplantation.Methods The pharmacist was on duty at the organ transplant outpatient clinic.During this time,they analyzed and sorted out the medications,identified and differentiated a case of asymptomatic hyperuricemia related to spironolactone in a patient who had undergone a renal transplant,and provided comprehensive care throughout the entire process.Results The asymptomatic hyperuricemia in this patient might be associated with spironolactone,and the adverse reactions of the patient were alleviated by pharmacists through optimizing clinical treatment.Up to now,no hyperuricemia occurred.Conclusions Pharmacists are required to collaborate closely with clinicians to establish medication profiles for patients under long-term follow-up and to closely monitor and evaluate drug-related adverse reactions.Additionally,they should assess the renal function and immune status of transplant recipients promptly and formulate individualized treatment plans in order to enhance the long-term survival of both the transplanted kidneys and the recipients.
