Treatment Analysis of Voriconazole Combined with Cyclosporine Induced Aplastic Anemia in Children with Acute Kidney Injury
10.3870/j.issn.1004-0781.2025.10.008
- VernacularTitle:伏立康唑联合环孢素致再生障碍性贫血患儿急性肾损伤的治疗分析
- Author:
Yuanyuan YUE
1
;
Danli ZHOU
1
;
Yanhua CHEN
1
;
Yan WANG
1
Author Information
1. 江南大学附属儿童医院(无锡市儿童医院)药学部,无锡 214023
- Publication Type:Journal Article
- Keywords:
Voriconazole;
Cyclosporine;
Aplastic anemia;
Acute kidney injury;
Therapeutic drug monitoring;
Adverse drug reactions
- From:
Herald of Medicine
2025;44(10):1572-1575
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pharmaceutical monitoring for children with acute kidney injury caused by voriconazole combined with cyclosporine,in order to provide methods and ideas for clinical pharmacists to conduct pharmaceutical services.Methods The clinical pharmacist assisted physicians to analyze the causes of two episodes of abnormal renal function in the children,and used the therapeutic drug monitoring to monitor the whole process of medication.Results The child's acute kidney injury was likely to be related to medication,and physicians adopted the pharmacist's recommendation for therapeutic drug monitoring and drug adjustment,and the child didn't have any renal function abnormalities again.Conclusion Clinical pharma-cists can use pharmacokinetic knowledge and therapeutic drug monitoring methods to assist physicians in formulating and optimi-zing treatment plans,and monitor the whole process of medication for special children to ensure safety medication.
