Ethical Challenges and Response Strategies in Drug Development for Radiation Prevention and Control
- VernacularTitle:辐射防治药物研发中的伦理挑战与应对策略
- Author:
Li ZHANG
1
;
Ding LI
1
;
Chang LU
1
;
Peng ZHANG
1
;
Ran ZHANG
1
;
Ge WANG
1
;
Liping YANG
1
;
Rui HU
1
;
Jian GONG
1
Author Information
- Publication Type:Journal Article
- Keywords: Ionizing radiation; Radiation hazards; Radiation protective drug; Ethical challenges; Animal experiments; Human trials
- From: Herald of Medicine 2025;44(10):1632-1637
- CountryChina
- Language:Chinese
- Abstract: Excessive ionizing radiation can disrupt the molecular structures of organisms,leading to health issues such as acute radiation syndrome and cancer,posing serious threats to human health.The development of radioprotective drugs holds significant importance for mitigating ionizing radiation damage and safeguarding public health,yet its research process faces multidimensional ethical challenges.This paper systematically explores the ethical issues involved in the full lifecycle of radioprotective drug development,focusing on the ethical particularities of animal experimentation,ethical dilemmas in human trials,data privacy and security risks,as well as challenges in managing conflicts of interest.Targeted solutions are proposed,including strengthening ethical review mechanisms,promoting interdisciplinary collaboration,constructing data security management systems,and establishing conflict-of-interest mediation mechanisms.These comprehensive measures aim to build a scientifically rigorous ethical framework for radioprotective drug research,fostering sustainable development in this field.
