Analysis of the vaccination of people treated with assisted reproductive technology
10.3760/cma.j.cn101441-20221222-00583
- VernacularTitle:接受辅助生殖技术治疗人群的新冠疫苗接种情况分析
- Author:
Lixue CHEN
1
;
Yijian FAN
;
Rong LI
;
Hongping WU
Author Information
1. 北京大学第三医院妇产科生殖医学中心 北京市人类辅助生殖技术质量控制和改进中心 国家妇产疾病临床医学研究中心 辅助生殖教育部重点实验室（北京大学）生殖内分泌与辅助生殖技术北京市重点实验室，北京100191
- Publication Type:Journal Article
- Keywords:
Reproductive techniques, assisted;
COVID-19 vaccines;
Vaccination coverage
- From:
Chinese Journal of Reproduction and Contraception
2023;43(5):513-518
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore whether the vaccination of COVID-19 vaccine affects the clinical pregnancy rate of assisted reproductive technology (ART).Methods:Based on a cross-sectional design, 17 611 cycles of ART treatment in 12 human-assisted reproductive institutions under Beijing Municipality from August 1, 2021, to July 31, 2022 were investigated, and their vaccination status and clinical pregnancy rate were investigated and analyzed.Results:The new crown vaccination rates of men and women receiving ART treatment were 58.83% (10 361/17 611) and 41.46% (7 301/17 611), respectively; 80.88% (5 864/7 250) of the couples did not complete the vaccination due to concerns about the safety or adverse reactions of the vaccine. The results of univariate analysis and logistic multivariate analysis showed whether vaccination with the new crown vaccine will not significantly affect the clinical pregnancy rate of artificial insemination or in vitro fertilization and embryo transfer (IVF-ET). The clinical pregnancy rate of fully vaccinated under artificial insemination was 10.74% (100/931), which was 11.10% (206/1 856) of both not vaccinated, there was no significant difference ( P=0.776), while adjusted OR=0.96, 95% CI: 0.74-1.24, P=0.766. The clinical pregnancy rate of fully vaccinated under IVF-ET was 41.88% (2 450/5 850), both not vaccinated was 40.92% (1 815/4 435), there was no significant difference ( P=0.330), while adjusted OR=1.02, 95% CI: 0.94-1.11, P=0.578. Conclusion:Vaccination against COVID-19 does not affect the clinical pregnancy rate of ART treatments. The low vaccination rate of the childbearing age group who needs to assist in pregnancy needs more attention.
