The value of ZOOMit intravoxel incoherent motion diffusion weighted imaging technology in assessing renal function in diabetic kidney disease and non-diabetic kidney disease
10.3969/j.issn.1002-1671.2025.10.020
- VernacularTitle:ZOOMit体素内不相干运动扩散加权成像技术在评估糖尿病肾病与非糖尿病肾病肾功能的价值
- Author:
Xuesong LI
1
;
Qingjuan ZHANG
;
Qingqing ZHOU
;
Yusheng YU
;
Hong ZHANG
;
Hui LI
Author Information
1. 南京医科大学附属江宁医院医学影像科,江苏 南京 211100
- Publication Type:Journal Article
- Keywords:
intravoxel incoherent motion diffusion weighted imaging;
diabetic kidney disease;
non-diabetic kidney disease;
kidney function assessment
- From:
Journal of Practical Radiology
2025;41(10):1689-1693
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of ZOOMit intravoxel incoherent motion diffusion weighted imaging(IVIM-DWI)technology in assessing renal function in diabetic kidney disease(DKD)and non-diabetic kidney disease(non-DKD).Methods Based on the estimated glomerular filtration rate(eGFR),50 DKD patients and 50 non-DKD patients were enrolled,with each group contained 21 mild cases(mild group)and 29 moderate to severe cases(moderate to severe group).All subjects underwent ZOOMit IVIM-DWI examination and the parameter values of the renal cortex and medulla were measured.The differences of IVIM-DWI parameters in renal cortex and medulla between DKD and non-DKD patients,and the correlation with eGFR,and diagnostic efficacy were compared.Results In the DKD patients,the f value of the medulla,the D value of the cortex,and the D* value of the medulla showed statistically significant differences between mild group and moderate to severe group(t=7.836,3.337,2.515,P<0.05),and all were positively correlated with eGFR(r=0.750,0.375,0.404,P<0.05).In the non-DKD patients,the f value of the medulla and the D* value of the medulla showed statistically significant differences between mild group and moderate to severe group(t=2.619,2.453,P<0.05),and were positively correlated with eGFR(r=0.425,0.360,P<0.05).In both DKD and non-DKD patients,the f value of the medulla showed the best efficacy in distinguishing between mild and moderate to severe DKD,with the area under the curve(AUC)=0.961(DeLong test P<0.05).Conclusion ZOOMit IVIM-DWI technology can be used for renal function in DKD and non-DKD,with the f value of the medulla being more suitable for the assessment of renal function in DKD.
