Progress in genetic research of non-obstructive azoospermia
10.3760/cma.j.cn101441-20230228-00072
- VernacularTitle:非梗阻性无精子症的遗传学研究进展
- Author:
Chong XIE
1
;
Yunhao WU
1
;
Fei SUN
1
Author Information
1. 浙江大学医学院附属邵逸夫医院男科(男性生殖与性医学中心）/泌尿外科，杭州 310020
- Publication Type:Journal Article
- Keywords:
Infertility, male;
Non-obstructive azoospermia;
Genetic research
- From:
Chinese Journal of Reproduction and Contraception
2023;43(5):468-472
- CountryChina
- Language:Chinese
-
Abstract:
Non-obstructive azoospermia (NOA) is a serious problem that plagues infertile men all over the world, but its specific genetic pathogenic factors are not completely clear at present. In recent years, with the continuous deepening of research on bioinformatics and genetics, more and more pathogenic genes have been found. The objects of genetic research on NOA mainly include chromosome abnormality, chromosome microdeletion, gene mutations and epigenetic modifications. In this paper, we have made a simple summary and evaluation of these findings, which will help you further understand the progress of genetic research on NOA.
