A case report of anaphylactic shock in a patient undergoing perioperative surgery due to cisatracurium besylate
10.12173/j.issn.1005-0698.202504116
- VernacularTitle:顺阿曲库铵致围手术期患者过敏性休克1例
- Author:
Jiqing XIE
1
;
Yanru KONG
;
Xiaowen MA
;
Huixia WANG
;
Yubo DONG
;
Dehui LIU
Author Information
1. 中国人民解放军联勤保障部队第九六○医院药剂科(济南 250031)
- Publication Type:Journal Article
- Keywords:
Cisatracurium besylate;
Anaphylactic shock;
Adverse drug reactions
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(10):1224-1227
- CountryChina
- Language:Chinese
-
Abstract:
A 42-year-old male patient developed mild allergic symptoms after the use of cisatracurium besylate in laparoscopic left renal tumor resection,which was relieved by symptomatic treatment.When the drug was added again intraoperatively,the patient's blood pressure decreased sharply from 120/71 mmHg to 50/30 mmHg,and the airway resistance increased from 16 cmH2O to 38 cmH2O,and the patient developed typical signs of anaphylactic shock.After immediate intravenous injection of epinephrine,calcium chloride and other drugs,the patient's blood pressure rose to 95/57 mmHg,airway resistance decreased to 20 cmH2O,and vital signs tended to be stable.The Naranjo's Assessment Scale was used to evaluate and analyze the correlation of suspected drugs.The score was 9 points,indicating that the association between anaphylactic shock and cisatracurium besylate in this patient was judged to be"definitely related".This article suggests that cisatracurium besylate carries an allergic risk and should be used with caution,and the monitoring of vital signs and allergic reactions should be strengthened for early identification and timely treatment to ensure the safety of patients during the perioperative period.
