The clinical outcomes analysis of drug-coated balloon de novo coronary lesions left with untreated dissection
10.3969/j.issn.1004-8812.2025.10.004
- VernacularTitle:冠状动脉原位原发病变经药物涂层球囊处理后未经治疗的遗留夹层临床结局
- Author:
Zhi-yuan CHENG
1
;
Wen-rui MA
1
;
Zi-lei PAN
1
;
Chang-sheng NAI
1
;
Shang CHANG
1
;
Li LIANG
1
;
Yao-jun ZHANG
1
;
Qian LI
1
Author Information
1. 徐州市肿瘤医院 徐州市第三人民医院心血管内科,江苏徐州 221000
- Publication Type:Journal Article
- Keywords:
Drug-coated balloon;
Coronary artery dissection;
De novo coronary lesions
- From:
Chinese Journal of Interventional Cardiology
2025;33(10):568-573
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical prognosis of untreated residual coronary artery dissection treated with drug coated balloon(DCB).Methods A retrospective analysis was conducted on the clinical and imaging data of patients with primary coronary artery lesions(2.5-4.0 mm)treated with DCB under angiography guidance at Xuzhou Cancer Hospital,Xuzhou New Health Geriatric Hospital,and Peixian Guotai Hospital from September 2017 to April 2023.According to the observation of coronary artery dissection through angiography,the patients were divided into a dissection group and a non dissection group.The main endpoint of this study was the major adverse cardiovascular event(MACE)during a 12-month follow-up.Results A total of 381 patients were enrolled in the three research centers,with 30 cases(30 lesions)in the dissection group and 351 cases(367 lesions)in the non dissection group.There was no significant difference between the two groups in terms of age,gender,hypertension,hyperlipidemia,diabetes,smoking,previous myocardial infarction,previous percutaneous coronary intervention,coronary artery bypass grafting and other baseline clinical characteristics(all P＞0.05).Except for the reference vessel diameter(P=0.049)and DCB pressure(P=0.032),there was no statistically significant difference in the characteristics of coronary angiography lesions between the two groups of patients(both P＞0.05).During a 12-month follow-up,there was no statistically significant difference(P＞0.05)in the incidence of MACE between the dissection group and the non dissection group after DCB treatment for primary coronary artery lesions in situ.Conclusions Untreated residual dissection after DCB treatment of de novo coronary lesions does not lead to an increase in clinical MACE.
