A denoising method for low-dose CT images based on MDC-DCRN model
10.3969/j.issn.1005-202X.2025.09.003
- VernacularTitle:一种基于MDC-DCRN模型的低剂量CT图像去噪方法
- Author:
Hongchi CHEN
1
;
Ying ZHAI
1
;
Qiuxia LI
1
;
Fangzuo LI
1
Author Information
1. 赣南医科大学医学信息工程学院,江西 赣州 341000;赣南医科大学心脑血管疾病防治教育部重点实验室,江西 赣州 341000;组织工程江西省重点实验室(2024SSY06291),江西 赣州 341000
- Publication Type:Journal Article
- Keywords:
low-dose CT;
deep learning;
perceptual loss;
image denoising;
artifact reduction
- From:
Chinese Journal of Medical Physics
2025;42(9):1136-1146
- CountryChina
- Language:Chinese
-
Abstract:
Objective Low-dose CT(LDCT)images significantly affect clinical diagnosis due to the substantial presence of noise and artifacts.To address the challenges such as over-smoothing of images,loss of texture details,and the presence of residual noise artifacts,a deconvolution-convolution residual network integrating multi-scale dilated convolution(MDC-DCRN)is proposed for LDCT denoising.Methods The network employed deconvolution-convolution architecture to better preserve image details and integrated an MDC module to enhance the feature extraction capabilities at different scales.Moreover,the issue of excessive image smoothing was effectively mitigated by the composite loss function combining L1 loss and perceptual loss.Results The experimental results on the Mayo dataset demonstrated that MDC-DCRN outperformed 4 classic denoising methods,namely RED-CNN,EDCNN,WGAN-RAM,and CTformer.MDC-DCRN effectively eliminated noise and artifacts while recovering more texture detail information.Compared with LDCT images,the images processed by MDC-DCRN had an average increase of 13.64%in peak signal-to-noise ratio,an average increase of 4.57%in structural similarity index,and an average decrease of 37.40%in root mean square error.Conclusion The proposed MDC-DCRN model can effectively preserve details while reducing noise from low-dose scanning,offering a novel approach to clinical LDCT image denoising.
