Current status and influencing factors of tuberculosis infection in health-care workers in designated tuberculosis medical institutions in Yantai City
10.12138/j.issn.1671-9638.20252307
- VernacularTitle:烟台市结核病定点医疗机构医务人员结核感染现状及影响因素
- Author:
Lili ZHEN
1
;
Jingyu LIU
;
Jing ZHOU
;
Xiaoyun LAN
;
Hongren WANG
;
Shichao SHANG-GUAN
;
Yuelei WANG
Author Information
1. 烟台市疾病预防控制中心结核病防制科,山东 烟台 264003
- Publication Type:Journal Article
- Keywords:
tuberculosis;
latent infection;
healthcare worker;
recombinant Mycobacterium tuberculosis fusion protein
- From:
Chinese Journal of Infection Control
2025;24(10):1435-1442
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the prevalence of latent tuberculosis infection(LTBI)among relevant healthcare workers(HCWs)in designated tuberculosis medical institutions(MIs)in Yantai City,and explore its influencing factors.Methods The cluster random sampling method was adopted to select two county-and district-level desig-nated tuberculosis MIs.All HCWs underwent questionnaire survey and creation tuberculin skin test(C-TST)at the same time,and the influencing factors for LTBI were analyzed.Results A total of 215 HCWs from designated tu-berculosis MIs were included for analysis,37 were diagnosed with LTBI,with an infection rate of 17.21%(95%CI:12.42%-22.93%).Multivariate logistic regression analysis showed that clinicians(OR=3.19,95%CI:1.05-9.69),laboratory technician(OR=5.90,95%CI:1.21-28.77),working years≥10 years(OR=3.31,95%CI:1.39-7.90),and tuberculosis history of family members(OR=6.49,95%CI:1.01-41.46)were independent risk factors for LTBI.Conclusion The infection risk of clinicians and laboratory technicians who directly contact with tuberculosis patients or Mycobacterium tuberculosis is higher than that of other HCWs,and is related to the length of working years.It is suggested that healthcare-associated infection control measures should be streng-thened,and tuberculosis active screening should be carried out regularly for HCWs in key departments.