Selection of health utility measurement tools for high-risk populations with cardiovascular disease:Application validation of EQ-5D-5L and SF-6Dv2
10.3969/j.issn.1674-2982.2025.08.003
- VernacularTitle:心血管病高危人群健康效用测量工具的选择:EQ-5D-5L与SF-6Dv2的应用验证
- Author:
Ju SUN
1
;
Qian GUO
;
Hao-miao LI
;
Qiang YAO
;
Shu-zhen ZHU
;
Jun-lin LI
Author Information
1. 武汉大学政治与公共管理学院 湖北 武汉 430072;武汉大学健康治理研究中心 湖北 武汉 430072
- Publication Type:Journal Article
- Keywords:
Cardiovascular Diseases;
EQ-5D-5L;
SF-6Dv2;
Health utility value
- From:
Chinese Journal of Health Policy
2025;18(8):20-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective:In the context of China's cardiovascular disease(CVD)high-risk population screening and intervention project,this study systematically evaluates the applicability of the EQ-5D-5L and SF-6Dv2 instruments among individuals at high risk of CVD.Methods:Convergent validity was assessed using Spearman's correlation coefficient.Measurement agreement was evaluated through intraclass correlation coefficients(ICC)and Bland-Altman plots.Factors influencing utility differences were explored using multiple linear regression analysis.Kruskal-Wallis test and t-test were used to examine discriminant validity.Sensitivity was compared by effect size(ES),relative efficiency(RE),and the area under the receiver operating characteristic curve(ROC-AUC).Floor and ceiling effects were also compared.Results:Among 5,415 individuals at high risk of CVD,the two instruments showed moderate overall correlation and acceptable convergent validity,but dimension-specific correlations were weak,and measurement consistency was low(ICC=0.367).Both instruments effectively distinguished different health states,yet the SF-6Dv2 demonstrated superior sensitivity and a milder ceiling effect.Conclusion:When measuring the health utility value of CVD patients,scale selection should be cautious,especially for high-risk groups,and SF-6Dv2 is more appropriate.
