Practice and efficacy of nursing staff's participation in antimicrobial ste-wardship
10.12138/j.issn.1671-9638.20252454
- VernacularTitle:护理人员参与抗菌药物科学化管理的实践与效果
- Author:
Cheng ZHANG
1
;
Milan ZHONG
;
Weiyi HUANG
;
Keke WANG
;
Yun ZHANG
;
Liangzhi JIANG
;
Lijun QIU
Author Information
1. 上海市杨浦区中心医院(同济大学附属杨浦医院)医院感染管理科,上海 200090
- Publication Type:Journal Article
- Keywords:
antimicrobial stewardship;
nursing staff;
antimicrobial agent;
rational use;
AMS
- From:
Chinese Journal of Infection Control
2025;24(9):1314-1320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the intervention effect of nursing staff's participation in antimicrobial stewardship(AMS)on the rational use of antimicrobial agents,and explore its role in constructing a scientific healthcare-associa-ted infection(HAI)control management.Methods The data on perioperative prophylactic use of antimicrobial agents,surgical-related HAI control,and pathogen detection before therapeutic use of antimicrobial agents among hospitalized patients in a hospital from January 2016 to December 2024 were collected.Relevant evaluation indica-tors before and after nursing staff participating in AMS were compared.2016-2018,2019-2021,and 2022-2024 were stages before intervention,during intervention,and after intervention,respectively.Results After nursing staff participated in AMS,the use rate of prophylactic antimicrobial agents 0.5-1 hour before surgery and discon-tinuation rate of antimicrobial agents within 24 hours after class Ⅰ incision surgery increased from 64.54％and 81.41％before intervention to 75.31％and 84.56％after intervention,respectively.Incidences of surgical-related HAI and surgical site infection in patients decreased from 3.11％and 0.96％before intervention to 1.37％and 0.17％after intervention,respectively.Pathogen detection rates before restricted-and special-grade antimicrobial agents treatment increased from 50.80％and 68.70％before intervention to 55.19％and 80.53％after interven-tion,respectively.Proportion of blood specimen from which coagulase-negative Staphylococcus was detected de-creased from 29.30％before intervention to 21.26％after intervention.Proportion of respiratory specimen from which Haemophilus influenzae was detected increased from 2.00％to 3.98％.Differences were all statistically sig-nificant(all P＜0.05).Conclusion As important members of the AMS team,nursing staff can effectively reduce irrational antimicrobial use,optimize medication timing and duration,and have a positive effect on ensuring patient safety through participating in the use and management of antimicrobial agents in hospitalized patients.
