Inflammatory myofibroblastic tumor of the bladder:report of two cases and literature review
10.3969/j.issn.1009-8291.2025.10.011
- VernacularTitle:膀胱炎性肌纤维母细胞瘤2例报道并文献复习
- Author:
Junhao CHU
1
;
Weihai CHONG
;
Zhihui ZHANG
;
Jiajun KAN
;
Jiwei ZHAI
;
Muwen WANG
Author Information
1. 山东第一医科大学附属山东省立医院泌尿外科,山东济南 250021
- Publication Type:Journal Article
- Keywords:
bladder tumor;
inflammatory myofibroblastic tumor;
transurethral en bloc resection of bladder tumor;
laparoscopic partial cystectomy
- From:
Journal of Modern Urology
2025;30(10):875-880
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize and evaluate the treatment strategies and clinical outcomes of bladder inflammatory myofibroblastic tumor(IMT),so as to provide reference for the diagnosis and treatment of this rare entity.Methods A retrospective analysis was conducted on the clinical data of two patients with bladder IMT treated at Shandong Provincial Hospital Affiliated to Shandong First Medical University.In combination with literature analysis,the clinical characteristics,treatment methods and prognosis of this disease were analyzed.Results Both patients presented with painless terminal macroscopic hematuria.Patient 1 was a 42-year-old male with a 6 cm bladder mass detected by cystoscopy,with no muscular involvement.Transurethral en bloc resection with a 1470 nm diode laser was performed,followed by a second transurethral resection.Patient 2 was a 21-year-old male with a 5 cm bladder mass visualized on cystoscopy,with no muscular invasion.Transurethral en bloc resection using a 1470 nm diode laser was conducted,followed by transurethral laser marking the margin of the wound and laparoscopic partial cystectomy.Preoperative cystoscopic biopsy and postoperative pathology diagnosed it as IMT,which invaded the superficial muscular layer and the margin was negative.Patient 1 was followed for 40 months and patient 2 for 15 months.Follow-up cystoscopy performed every 3 months showed no evidence of recurrence.This article also summarized the relevant literature on bladder IMT over the past five years.Conclusion Bladder IMT is an extremely rare neoplasm with nonspecific clinical manifestations,posing challenges in both diagnosis and treatment.However,early recognition and definitive pathological diagnosis,combined with bladder-sparing surgical strategies such as en bloc resection,often result in favorable outcomes,with reduced risk of recurrence and improved quality of life.
