Progress in role of exosomes in adenovirus pneumonia in children
10.3969/j.issn.1000-4718.2025.10.023
- VernacularTitle:外泌体在儿童腺病毒肺炎中的研究进展
- Author:
Wenjin FENG
1
;
Huanqi TANG
;
Huabin WANG
Author Information
1. 山东中医药大学第二临床医学院,山东 济南 250355;济宁医学院附属医院儿科,济宁市儿童重症感染防治重点实验室,山东 济宁 272000
- Publication Type:Journal Article
- Keywords:
exosomes;
adenovirus;
pneumonia;
children
- From:
Chinese Journal of Pathophysiology
2025;41(10):2059-2063
- CountryChina
- Language:Chinese
-
Abstract:
Adenoviruses are the main pathogens causing acute respiratory tract infection in infants and young children,and adenovirus types 3 and 7 infections often develop into severe pneumonia,which seriously threatens chil-dren's health and affects their quality of life.Exosomes are extracellular vesicles that possess a phospholipid bilayer struc-ture.Exosomes can be secreted and synthesized by various cells and can carry a variety of bioactive substances,such as nucleic acids and proteins.The occurrence and release of exosomes are closely related to the physiological functions of the body's cells.In recent years,studies have shown that exosomes released by patients with adenovirus infection play crucial roles in transmission and immune response activation against the virus.Therefore,in-depth research on exosomes and ade-noviruses provides new directions for the diagnosis,treatment,and clinical drug development of paediatric adenovirus pneumonia.
