Research progress of microecological changes in endometriosis and its effect on fertility
10.3760/cma.j.cn101441-20220609-00253
- VernacularTitle:子宫内膜异位症微生态改变及其对生育力影响的研究进展
- Author:
Yanhong XU
1
;
Zhen HOU
1
;
Yundong MAO
1
Author Information
1. 南京医科大学第一附属医院生殖医学中心 生殖医学国家重点实验室,南京 210029
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Microbiota;
Fertility
- From:
Chinese Journal of Reproduction and Contraception
2023;43(6):646-649
- CountryChina
- Language:Chinese
-
Abstract:
Endometriosis (EMS) is a common gynecological disease, usually occurs in women of reproductive age. EMS is characterized by pelvic pain, infertility and sexual discomfort, which seriously affects women's physical and mental health. There are a large number of microorganisms in various parts of the human body, which play an important role in various stages of reproduction through the microbial community itself or metabolites. Recent studies have found changes in the composition of microbiota in patients with EMS, and the effect of EMS on female fertility is closely related to imbalances in the human microecological environment. This article reviews the interaction between female microbiome and EMS, and the relationship between changes in microecological environment and adverse pregnancy outcomes in EMS patients.