Associations of dietary patterns and osteoporosis in patients with knee osteoarthritis:a correlation study
10.3969/j.issn.1671-8283.2025.09.005
- VernacularTitle:膝骨关节炎患者膳食模式与骨质疏松症的相关性研究
- Author:
Xiaoni ZHOU
1
;
Peihua CAO
;
Peichun GAO
;
Yuting QIN
;
Jianjin WANG
;
Linxin XIE
;
Ao WU
;
Changhai DING
;
Hongzhen XIE
Author Information
1. 长江大学医学部,湖北 荆州,434023;南方医科大学珠江医院临床研究中心,广东 广州,510282
- Publication Type:Journal Article
- Keywords:
knee osteoarthritis;
osteoporosis;
bone mineral density;
dietary patterns;
Pearl River osteoarthritis cohort
- From:
Modern Clinical Nursing
2025;24(9):34-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the associations of dietary patterns with bone mineral density(BMD)and osteoporosis(OP)in patients with knee osteoarthritis(KOA)in south China,identify the dietary patterns that could reduce the risk of OP,and provide a reference for prevention of OP.Methods Data from 600 KOA patients who were enrolled in the Pearl River Osteoarthritis Cohort(PROC)between April 2020 and April 2024 were extracted,including general characteristics,dietary questionnaire and BMD test.Factor analysis was employed to identify dietary patterns.Scores of dietary pattern were treated as continuous or categorical variables(quartile-based groups).Multivariable linear regression was used to assess associations between scores of dietary pattern and BMD,while the relationships with OP were analysed by binary logistic regression.Results The prevalence of OP in KOA patients was 19.8%.Factor analysis extracted eight dietary patterns:seafood-nuts,livestock-poultry meats,coarse grains-fruits,wheat-eggs,fish-dairy-vegetables,legumes-fruits,rice-wheat flour,and soy-dairy.After adjusting for confounders,it was found that the pattern of coarse grains-fruits was positively correlated with the BMD of left femoral neck and lumbar spine(P<0.01)and the fish-dairy-vegetables pattern was positively correlated with the BMD of lumbar spine(P<0.01).When pattern scores were discretized into quartiles,the legumes-fruits pattern(Q3 vs.Q1)was found in association with a 68.2%reduction in the risk of OP(P<0.05).Conclusion This study has identified that the pattern of legumes-fruits may lower a risk of OP,while the patterns of coarse grains-fruits and fish-dairy-vegetables correlate with higher BMD.The diet patterns are potentially beneficial to prevention of OP.For bone health,a balanced diet rich in legumes,fruits,vegetables,coarse grains,fish,nuts and dairy is recommended.
