Recent Advances in the Treatment of Inflammatory Peripheral Neuropathy
10.3870/j.issn.1672-0741.25.04.037
- VernacularTitle:炎症性周围神经病的治疗新进展
- Author:
Choi KALAM
1
;
Jinyi YAN
1
;
Peicai FU
1
Author Information
1. 华中科技大学同济医学院附属同济医院神经内科,武汉 430030
- Publication Type:Journal Article
- Keywords:
inflammatory peripheral neuropathy;
therapeutic advances;
biologics;
immunosuppressant
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2025;54(5):726-733
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory peripheral neuropathy,also known as immune-mediated peripheral neuropathy,is a rare group of heterogeneous peripheral neuropathy characterized by dysfunction and damage to different structures of the peripheral nerves,including Guillain-Barre syndrome,chronic demyelinating inflammatory polyradiculopathy,autoimmune neuropathy,multifocal motor neuropathy or neuropathy related to monoclonal gamma globulinopathy,etc.The causes of these diseases remain unclear,but B cells and autoantibodies play a key role in their pathogenesis.This group of diseases can be classified as having acute or chronic onset based on the mode of onset.Clinically,it can present as a unipolar course,recurrent or progressive course.Severe inflammatory peripheral neuropathy can lead to flaccid paralysis of the limbs,with a high risk of severe disability and death.With the rapid progress of various studies in the field of neuroimmunological diseases in recent years,the therapeutic tar-gets/methods for immune-mediated peripheral neuropathy have also presented a flourishing situation.The latest progress at home and abroad is summarized as follows.
