Infection Status and Genotype Analysis of Human Papillomavirus in 922 Males
10.3870/j.issn.1672-0741.25.04.017
- VernacularTitle:922例男性中人乳头瘤病毒的感染情况及基因型分析
- Author:
Shaowei LIU
1
;
Jun LUO
1
Author Information
1. 三峡大学第一临床医学院(宜昌市中心人民医院)检验科,宜昌 443003
- Publication Type:Journal Article
- Keywords:
human papillomavirus;
male;
epidemiology
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2025;54(5):714-719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the infection status and genotype distribution of human papillomavirus(HPV)in males in Yichang Central People's Hospital,Hubei Province.Methods Clinical data of 922 males who visited Yichang Central People's Hospital and underwent HPV nucleic acid testing from July 2022 to December 2024 were retrospectively collected and ana-lyzed.Results Among 922 males,347 cases were HPV positive,and the positive rate was 37.64％(the positive rate of single in-fection was 25.60％,and the positive rate of multiple infections was 12.04％).A total of 25 subtypes of HPV were detected,and the positive constituent ratios from high to low were HPV6,11,52,16,44,58,etc.The positive constituent ratios of low-risk,intermediate-risk and high-risk HPV types were 54.19％,3.90％and 41.91％respectively,and the difference was statisti-cally significant(P＜0.05).For comparison among age groups,the positive rates of HPV infection,multiple infection,simple low-risk infection,and mixed infection of high-risk,medium-risk,and low-risk types were all higher in the≥65 years old group(all P＜0.05).The positive rate of simple high-risk HPV infection was relatively high in the 45-54 age group(P＜0.05).For comparison within age groups,the positive rates of single HPV infection in the 25-34 age group,the 35-44 age group,and the 45-54 age group were all higher than those of multiple infections(all P＜0.05).The positive rate of simple high-risk HPV in-fection was higher in the 45-54 age group,and the positive rate of simple low-risk HPV infection was higher in the other age groups(all P＜0.05).The positive rate of HPV in patients with warts was 67.32％,and the main subtypes were HPV6,11,16,44.The positive rate of HPV in patients with urinary tract infection was 25.61％,and the main subtypes were HPV6,52,58,16.The positive rate of HPV in fertility examination was 41.94％,and the main subtypes were HPV52 and 58.The positive rate of HPV in health examination was 19.02％,and the main subtypes were HPV52,16 and 51.Conclusion HPV infection in males in our hospital is mainly a single infection.HPV6,11,52,16,44 and 58 were the most common.Low-risk HPV has a rela-tively high proportion of infections.The positive rate of HPV infection is relatively high among the middle-aged and elderly groups.Warts,rashes and balanitis were mainly simple low-risk HPV infection.Urinary tract infection,fertility examination and physical examination were mainly high-risk HPV infection.
