Correlation between neutrophil percentage-to-albumin ratio and coronary lesion severity and prognosis in patients with acute coronary syndrome
10.12007/j.issn.0258-4646.2025.10.007
- VernacularTitle:急性冠脉综合征患者中性粒细胞百分比与白蛋白比值与冠状动脉病变程度及预后的相关性
- Author:
Xinran LIU
1
;
Jingru MA
1
Author Information
1. 沈阳医学院附属第二医院心血管内科,沈阳 110035
- Publication Type:Journal Article
- Keywords:
neutrophil percentage-to-albumin ratio;
acute coronary syndrome;
coronary lesion severity;
major adverse cardiovascular event
- From:
Journal of China Medical University
2025;54(10):902-906,913
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of neutrophil percentage-to-albumin ratio(NPAR)on coronary lesion severity and short-term major adverse cardiovascular events(MACE)in patients with acute coronary syndrome(ACS).Methods The study included 345 newly diagnosed patients with ACS at the Second Hospital Affiliated to Shenyang Medical College from January 2020 to December 2023.NPAR was calculated,and the patients were divided into low,medium,and high NPAR groups using a tertile classification.Clinical data,including the coronary lesion Gensini score(GS),as well as the incidence of MACE during follow-up at various time points within one year,were compared among the three groups.Results The CS was significantly higher in the high NPAR group than in the low and medium groups.Spearman's analysis showed the strongest correlation between NPAR and GS(r=0.427,P＜0.001).Multiple linear regression analysis indicated that NPAR,body mass index,white blood cell count,and age were independent risk factors for increased GS.NPAR greater than 2.013 indicates a good predictive value for the incidence of MACE within 30 days,with the receiver operating cha-racteristic and area under the curve of 0.811.Conclusion The severity of coronary lesions in patients with ACS is positively correlated with NPAR,and a high NPAR can effectively predict the risk of MACE within 30 days.
