Research progress on risk factors of monozygotic twins in assisted reproductive technology
10.3760/cma.j.cn101441-20210930-00445
- VernacularTitle:辅助生殖技术单卵双胎风险因素研究进展
- Author:
Na CHEN
1
;
Jingyu LI
1
;
Linlin CUI
1
Author Information
1. 山东大学生殖医学研究中心（山东大学第二医院）生殖内分泌教育部重点实验室 山东省生殖医学重点实验室 山东省生殖健康临床医学研究中心 国家辅助生殖与优生工程技术研究中心，济南 250012
- Publication Type:Journal Article
- Keywords:
Twins, monozygotic;
Reproductive technology, assisted;
Fertilization in vitro;
Blastocyst transfer;
Inner cell mass
- From:
Chinese Journal of Reproduction and Contraception
2023;43(2):204-208
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of assisted reproductive technology since the 1970s, the incidence of multiple pregnancies has increased significantly, and the maternal and infant complications during pregnancy and postpartum caused by multiple pregnancies have received extensive public attention. Relevant investigations showed that the rate of monozygotic twins after assisted reproductive technology was higher than that of natural pregnancy, which not only increase the risk of neonatal related adverse outcomes, but also has a far-reaching impact on the long-term health of offspring. In order to understand the related risk factors and potential mechanisms of monozygotic twins after assisted reproductive technology better and provide intervention target for reducing the rate of monozygotic twins in clinic, we sorted out papers about the rate of monozygotic twins in assisted reproductive technology offspring and the effects of factors such as ovulation induction, ovum and embryo manipulation, and in vitro culture on the incidence of monozygotic twins.
