Effect of remote ischemic conditioning combined with binaural beat music training in patients with cognitive dys-function after cerebral infarction
10.3969/j.issn.1006-9771.2025.09.009
- VernacularTitle:远隔缺血适应联合双耳节拍音乐训练对脑梗死认知障碍的效果
- Author:
Xing XUE
1
;
Haiyan ZHAO
;
Shuling YUE
;
Jie CHENG
;
Qiqun TANG
;
Xiaohua CHENG
;
Zonghai GUO
;
Pingping LIU
Author Information
1. 华北理工大学,河北 唐山市 063210
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
remote ischemic conditioning;
binaural beat music;
cognitive dysfunction;
quality of life
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(9):1057-1065
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of remote ischemic conditioning(RIC)combined with binaural beat music(BBM)train-ing in patients with cognitive dysfunction after cerebral infarction.Methods From June,2024 to January,2025,200 patients with cognitive dysfunction after cerebral infarction in the Affil-iated Hospital of North China University of Science and Technology were randomly divided into control group(n=50),RIC group(n=50),BBM group(n=50)and combined group(n=50).All the groups received stan-dardized routine training,RIC group received RIC,BBM group received BBM,and the combined group received RIC+BBM,for 14 days.They were assessed with Montreal Cognitive Assessment(MoCA)and Stroke-Specific Quality of Life Scale(SS-QOL)at baseline,day 14,and day 90.Results Two cases in the control group,four in RIC group,three in BBM group and three in the combined group dropped out.For MoCA scores,the inter-group effect,intra-group effect and interaction effect were all significant(F>13.463,P<0.001).After intervention,on both day 14 and day 90,the score of MoCA was higher in each in-tervention group than in the control group(P<0.05),and was higher in the combined group than in both BBM and RIC groups(P<0.05);and on day 90,it was higher in RIC group than in BBM group(P<0.05).For SS-QOL,the score increased with time in all the groups(χ2>75.182,P<0.001).After intervention,there was signif-icant difference at each time point among four groups(H>18.260,P<0.001).On day 14 and day 90,the score of SS-QOL was higher in the combined group than in the control and BBM groups(|Z|>3.149,P<0.05);on day 90,the score was higher in RIC group than in the control group(|Z|=3.590,P<0.05),and it was higher in the combined group than in RIC group(|Z|=3.186,P<0.05).Conclusion RIC,BBM and their combination all improved cognitive function after cerebral infarction.RIC was superior to BBM,and the combined intervention yielded the greatest benefit.Both RIC and the combined intervention im-proved quality of life,with the combined approach being the most effective.
