Research advances of decidual macrophages in recurrent spontaneous abortion
10.3760/cma.j.cn101441-20200825-00461
- VernacularTitle:蜕膜巨噬细胞在复发性流产中的研究进展
- Author:
Ye SHANG
1
;
Saijiao LI
1
;
Jinli DING
1
;
Jing YANG
1
Author Information
1. 武汉大学人民医院生殖医学中心,湖北省辅助生殖与胚胎发育医学临床研究中心,武汉 430060
- Publication Type:Journal Article
- Keywords:
Recurrent spontaneous abortion;
Decidual macrophages;
Immunological tolerance
- From:
Chinese Journal of Reproduction and Contraception
2022;42(4):413-418
- CountryChina
- Language:Chinese
-
Abstract:
Recurrent spontaneous abortion is a clinical refractory infertility with complex etiology and nearly half of the causes are unexplained, which seriously affects the physical and mental health of patients. Decidual macrophages play an important role in embryo implantation, placenta formation, fetal development and delivery, and their number, function and phenotype are closely related to normal pregnancy. This article reviewed the research progress of decidual macrophages in recurrent spontaneous abortion.