Association of Arterial Elasticity with Left Ventricular Structure and Function
10.11969/j.issn.1673-548X.2025.09.014
- VernacularTitle:动脉弹性与左心室结构及功能的相关性分析
- Author:
Zhiran LIU
1
;
Bin CHEN
;
Xinru XU
Author Information
1. 200233 上海交通大学医学院附属第六人民医院超声医学科、上海超声医学研究所、上海市神经超声影像诊疗重点实验室
- Publication Type:Journal Article
- Keywords:
Brachial-ankle pulse wave velocity;
Transthoracic echocardiography;
Left ventricular structure;
Left ventricular func-tion
- From:
Journal of Medical Research
2025;54(9):79-85
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between brachial-ankle pulse wave velocity(baPWV)and left ventricular structure and function.Methods A total of 4864 participants who completed baPWV and transthoracic echocardiography from January 2010 to December 2021 were included.The participants were divided into three groups based on baPWV:Group T1:baPWV＜14m/s;Group T2:14m/s≤baPWV＜18m/s;Group T3:baPWV ≥18m/s.Multivariable Logistic regression and linear regression was used to examine the correlation between baPWV and interventricular septal thickness(IVS),left ventricular posterior wall thickness(LVPW),left ventricular end diastolic diameter(LVEDd),left ventricular mass index(LVMI),left ventricular ejection fraction(LVEF),and the presence of mitral e'/a'＜1.Results Increased baPWV was significantly associated with thickening of IVS(β=0.095,95％CI:0.007-0.182),thickening of LVPW(β=0.145,95％CI:0.056-0.233),and mitral e'/a'＜1(OR=2.200,95％CI:1.608-3.010)(P＜0.05).It was negatively correlated with LVEDd(β=-0.048,95％CI:-0.075--0.021)and showed no significant associa-tion with LVMI and LVEF(P＞0.05).Stratified analysis indicated that systolic blood pressure and baPWV had an interaction effect on LVEDd and mitral e'/a'＜1(P＜0.05).Conclusion BaPWV is associated with left ventricular remodeling and diastolic function.The correlation between baPWV and LVPW and LVEDd is stronger in groups with normal systolic blood pressure.In contrast,the correlation with mitral e'/a'＜1 is more prominent in groups with elevated systolic blood pressure.
