Evaluation of the evidence-based medicine of traditional Chinese medicine in the treatment of dry eye
10.13389/j.cnki.rao.2025.0153
- VernacularTitle:中医药治疗干眼的循证证据评价研究
- Author:
Juan LING
1
;
Xue HAN
;
Mei HU
;
Xue YANG
;
Jiajin LI
;
Mingli DAI
;
Jiayuan ZHUANG
;
Ying GAO
;
Yiming HU
;
Rui YANG
;
Li KANG
;
Xunwen LEI
;
Xiangxia LUO
Author Information
1. 730030 甘肃省兰州市,甘肃省人民医院;730030 甘肃省兰州市,甘肃中医药大学中医临床学院
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
dry eye;
evaluation of evidence-based evidence
- From:
Recent Advances in Ophthalmology
2025;45(11):888-896
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study aims to systematically evaluate the evidence-based medicine of traditional Chinese medicine(TCM)in the treatment of dry eye,analyze its efficacy and differences compared with modern Western medicine treatments,and provide a scientific basis for clinical application.Methods By searching Chinese and English databases(including CNKI,Wanfang Data,PubMed,Cochrane Library,etc.),we included meta-analyses and systematic reviews of TCM treatments for dry eye.Literature was screened according to strict inclusion and exclusion criteria,and relevant data were extracted and integrated for analysis.The Mantel-Haenszel fixed-effects model was used to calculate the relative risk(RR)and mean difference(WMD),with the effect size expressed as a 95％confidence interval,to analyze the efficacy in-dicators of TCM treatment for dry eye.Results A total of 21 articles were finally included,involving various TCM inter-ventions for dry eye(such as Chinese herbal medicine,acupuncture,and TCM external therapies).The results showed that TCM treatment was superior to Western medicine alone in improving the overall clinical efficacy[RR=1.63,95％CI(1.46,1.81),P＜0.05],prolonging tear film break-up time[MD=2.23,95％CI(1.85,2.60),P＜0.05],and increasing tear secretion[MD=1.49,95％CI(1.04,1.94),P＜0.05].In addition,acupuncture,the combination of Chinese herbal medicine and Western medicine,and TCM external therapies all demonstrated unique advantages in improving dry eye symptoms and tear function.Conclusion TCM treatment for dry eye shows significant efficacy in key indicators such as overall clinical efficacy,tear film break-up time,and tear secretion,with a high level of safety.
