Analysis of clinical and radiological characteristics of osteofibrous dysplasia
10.3969/j.issn.1002-1671.2025.09.024
- VernacularTitle:骨性纤维结构不良的临床及影像学特征分析
- Author:
Xiangya ZHANG
1
;
Guoyin CHENG
;
Yuke LIU
;
Wei CHEN
;
Qingqing HOU
Author Information
1. 河南省洛阳正骨医院(河南省骨科医院)影像中心,河南 洛阳 471000
- Publication Type:Journal Article
- Keywords:
osteofibrous dysplasia;
clinical manifestation;
imaging
- From:
Journal of Practical Radiology
2025;41(9):1533-1536
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and radiological features of osteofibrous dysplasia(OFD),and to improve the diagnostic accuracy of OFD and reduce the misdiagnosis rate.Methods A retrospective analysis was conducted on the clinical and radiological data of 21 patients with OFD confirmed by surgical pathology.Results Among the 21 patients,the imaging manifestations showed that the lesions were mainly located within the anterior cortex of the tibia,presenting as cystic expansile bone destruction with corti-cal expansion and thinning,protruding into the medullary cavity.Within the lesions,unequal thickness linear bony septations were visible,resembling soap-bubble changes,along with patchy ground-glass density shadow.A sclerotic rim was observed surrounding the lesions,with a clear boundary from normal tissue.No obvious soft tissue mass or periosteal reaction was noted in all cases.On MRI,the majority of the lesions exhibited prolonged T,and T2 signals,with linear hypointense separations observed within the lesions.No significant edema was noted in the surrounding bone and soft tissues,although a minor degree of bone marrow edema was present.All patients underwent surgical treatment.Fifteen patients were followed up for review,ranging from 3 to 38 months postoperatively.Among them,9 patients had no recurrence,while 6 patients experienced recurrence,manifesting as new lytic bone destruction in the surgical area.Conclusion The radiological manifestations of OFD are characteristic,and an accurate diagnosis can be made for typical cases in combination with the patient's age,location of the lesion and clinical presentation.Due to the high recurrence rate after OFD sur-gery,regular follow-up is recommended.
