Research progress on the effect of intrauterine infusion of hCG on embryo implantation
10.3760/cma.j.cn101441-20200511-00274
- VernacularTitle:宫腔灌注hCG对胚胎着床影响的研究进展
- Author:
Qimeng XIAO
1
;
Yuan LIU
1
;
Di SUN
1
;
Peiqin CHEN
1
;
Yue FU
1
;
Mingzhu BAI
1
;
Zhenbo ZHANG
1
Author Information
1. 上海交通大学附属第一人民医院辅助生殖中心200080
- Publication Type:Journal Article
- Keywords:
Intrauterine infusion;
Human chorionic gonadotropin;
Embryo implantation
- From:
Chinese Journal of Reproduction and Contraception
2021;41(7):655-660
- CountryChina
- Language:Chinese
-
Abstract:
Due to various factors, the proportion of infertile couples is increasing. In vitro fertilization-embryo transfer (IVF-ET) technology has made it possible for infertile couples to give birth. However, implantation failure has always hindered the development of IVF-ET. Embryo quality and endometrial receptivity are the keys to successful implantation. The implantation process is complicated and involves a variety of cytokines. Among them, human chorionic gonadotropin (hCG) plays an important role in the implantation process and even the entire pregnancy. At present, there are two opinions about whether hCG perfusion before embryo transfer affects the patient's pregnancy outcome: intrauterine infusion of hCG can improve the patient's pregnancy outcome; intrauterine infusion of hCG may not only not improve the patient's pregnancy rate, and even bring adverse consequences to the patient. But because there is no more uniform standard in the completed researches, the relationship between intrauterine infusion of hCG and embryo implantation is still inconclusive. Now, we summarize their contributions in this paper.
