The application value of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced MRI in preoperative assessment the differentiation degree of hepatocellular carcinoma
10.3969/j.issn.1002-1671.2025.09.018
- VernacularTitle:钆塞酸二钠增强MRI术前评估肝细胞癌分化程度的应用价值
- Author:
Shan GAO
1
;
Bin CHEN
;
Ying YANG
;
Xiaofeng HU
Author Information
1. 来安县人民医院影像科,安徽 滁州 239200
- Publication Type:Journal Article
- Keywords:
gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid;
hepatocellular carcinoma;
differentiation degree
- From:
Journal of Practical Radiology
2025;41(9):1508-1511
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the preoperative assessment of the differentiation degree of hepatocellular carcinoma(HCC),based on the imaging features observed on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd-EOB-DTPA)enhanced MRI HCC.Methods A retrospective analysis was conducted on the data of 198 patients with HCC confirmed by surgery or biopsy pathology,all of whom underwent Gd-EOB-DTPA enhanced examination before operation.According to pathological results,HCC patients were divided into poorly-differentiated group(group A,69 cases),moderately-differentiated group(group B,97 cases)and well-differentiated group(group C,32 cases).The signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),relative intensity ratio(RIR,,RIR2),and enhancement ratio(ER)of hepatobiliary phase HCC were calculated and analyzed.Results The CNR was the high-est in the group A and the lowest in the group C.Conversely,the SIHCC unenhanced,SIHCC hepatobiliary phase,and RIR1,RIR2 all were the highest in the group C and the lowest in the group A.There were statistically significant differences between the group C and the group B,as well as the group C and the group A(P＜0.05).Regarding signal characteristics during the hepatobiliary phase,the group A had the highest proportion of low/slightly low signal,while the group C had the lowest proportion.A statistically significant difference was observed between the group C and the group A(P＜0.05).Conclusion The Gd-EOB-DTPA enhanced MRI is helpful to preoperative assessment the differentiation degree of HCC.The higher the signal in the hepatobiliary phase,the smaller the CNR,the larger val-ues for the SIHCCunenhanced,SIHCC hepatobiliaryphase and RIR1,RIR2 are associated with the better the differentiation degree of HCC.
