Effect of functional electrical stimulation hand cycling on functional connection of brain networks in stroke pa-tients:a study based on functional near-infrared spectroscopy
10.3969/j.issn.1006-9771.2025.10.009
- VernacularTitle:功能性电刺激手摇车对脑卒中患者脑网络功能连接的功能性近红外光谱研究
- Author:
Sheng XU
1
;
Min ZHANG
;
Qingqing YANG
;
Qinglei WANG
;
Ayan GENG
;
Tong WANG
;
Chuan GUO
Author Information
1. 常州市德安医院,江苏 常州市 213004
- Publication Type:Journal Article
- Keywords:
stroke;
upper limb;
motor function;
functional electrical stimulation hand cycling;
functional near-infrared spectroscopy;
functional connection;
cortical function remodeling
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(10):1181-1187
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the potential central mechanisms of functional electrical stimulation(FES)hand cycling in promot-ing upper limb motor recovery after stroke.Methods A total of 35 stroke patients hospitalized in the Rehabilitation Center of Changzhou De'an Hospital from May,2023 to December,2024 were enrolled.They sequentially completed 10-minute FES hand cycling and 10-minute sham stimulation(simple hand cycling)tasks.The task order was randomized via dice rolling.Functional near-in-frared spectroscopy(fNIRS)was used to monitor real-time cerebral hemodynamic changes during both tasks to calculate the overall functional connectivity(FC)strength and the FC strength within regions of interest.Results The overall FC strength was higher during the FES hand cycling task than during the sham task(t=2.591,P<0.05),as well as FC between the ipsilateral primary motor cortex(iM1)and ipsilateral somatosensory association cortex(iSAC),iM1 and contralateral somatosensory association cortex(cSAC),ipsilateral pre-motor and supple-mentary motor cortex(iPMC)and iSAC,iPMC and cSAC,iPMC and ipsilateral primary somatosensory cortex(iS1),iPMC and iM1,and contralateral pre-motor and supplementary motor cortex(cPMC)and iSAC(PFDR<0.05).Conclusion FES hand cycling can promote the cortical function remodeling between cerebral hemispheres and the af-fected hemisphere,to integrate sensory-motor function.
