The value of CT combined with peripheral blood eosinophils in differentiating eosinophilic asthma and eosinophilic bronchitis
10.3969/j.issn.1002-1671.2025.09.010
- VernacularTitle:CT联合外周血嗜酸粒细胞在鉴别嗜酸粒细胞哮喘与嗜酸粒细胞性支气管炎中的价值
- Author:
Weicong CHEN
1
;
Ziyang XIA
1
;
Yaocheng WEN
1
;
Xin ZHENG
1
;
Qi WAN
1
;
Xinchun LI
1
Author Information
1. 广州医科大学附属第一医院放射科,广东 广州 510120
- Publication Type:Journal Article
- Keywords:
eosinophilic asthma;
eosinophilic bronchitis;
computed tomography;
peripheral blood eosinophils;
differential diagnosis
- From:
Journal of Practical Radiology
2025;41(9):1467-1471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of CT combined with peripheral blood eosinophils(EOS)for distinguishing eosinophilic asthma(EA)from eosinophilic bronchitis(EB).Methods The clinical characteristics,peripheral blood EOS detection and imaging features of 523 patients(328 cases of EA and 195 cases of EB)were retrospectively analyzed.Univariate analysis identi-fied statistically significant parameters,which were further utilized in binary logistic regression to construct an imaging model and a combined model incorporating clinical characteristics,peripheral blood EOS and imaging features.Receiver operating characteristic(ROC)curves were plotted to evaluate the performance of each model.Results Statistically significant differences were observed between the two groups in age,body mass index(BMI),peripheral blood EOS count,peripheral blood EOS percentage,and 11 ima-ging features,including bilateral lung,bronchial wall thickening and bronchial mucus plugs(P＜0.05).The area under the curve(AUC)of the imaging model and the combined model were 0.891 and 0.918,respectively.Conclusion The combined application of CT and peripheral blood EOS detection can improve the efficiency,simplicity,and accessibility of distinguishing EA from EB.
