Application value of MR three-dimensional double inversion recovery sequence in the diagnosis of optic neuritis
10.3969/j.issn.1002-1671.2025.09.006
- VernacularTitle:MR三维双反转恢复序列在视神经炎诊断的应用价值
- Author:
Hui ZHANG
1
;
Peng LIAN
;
Shijie JIANG
;
Peng LÜ
;
Daoqing WEI
;
Fengjun ZHAO
;
Lijuan YANG
;
Chenwang JIN
Author Information
1. 西安交通大学第一附属医院影像科,陕西 西安 710061;西安市人民医院 西安市第四医院医学影像中心,陕西 西安 710004
- Publication Type:Journal Article
- Keywords:
optic neuritis;
three-dimensional double inver-sion recovery;
diagnostic efficacy;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2025;41(9):1449-1452
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application value of the MR three-dimensional double inversion recovery(3D DIR)sequence in the diagnosis of optic neuritis(ON).Methods A retrospective analysis was conducted on MRI images from 40 patients with sus-pected ON.All patients underwent conventional T2 WI fat suppression(FS)and 3D DIR sequences.The lesion detection rate and diag-nostic accuracy of the intraorbital,intracanalicular,and intracranial segments of the optic nerve were compared between the two sequences,respectively.The receiver operating characteristic(ROC)curves were used to assess the diagnostic performance,and the intraclass correlation coefficient(ICC)were used to analyze interobserver consistency.Imaging assessments were independently performed by two senior and two junior radiologists.Results The sensitivity(SEN),specificity(SPE),and accuracy(ACC)in lesion detection of 3D DIR sequence were significantly better than those of conventional T2 WI FS sequence[odds ratio(OR)221 vs 104,P＜0.001].Notably,3D DIR sequence exhibited superior performance in detecting lesions in the intraorbital segment[area under the curve(AUC)0.915,OR=102]and intracanalicular segment(AUC 0.858,OR=51)compared with conventional T2WI FS sequence.Additionally,3D DIR sequence significantly improved diagnostic consistency among junior radiologists(ICC value increased from 0.469 to 0.655),bring-ing their diagnostic performance closer to that of senior radiologists(AUC improved to 0.883,ACC reached 90.1％).Conclusion The 3D DIR sequence has outstanding diagnostic efficacy in detecting ON lesions,significantly improving ACC and interobserver consistency,thereby offering strong support for the precise diagnosis of ON.
