Recent advances of double stimulation protocols in poor ovarian responders

VernacularTitle:双刺激方案在卵巢低反应患者中的应用研究进展
Author: Jingzhe LI ¹ ; Minzhi GAO ¹
Author Information

1. 上海交通大学医学院附属仁济医院生殖中心　上海市辅助生殖与优生重点实验室　200135
Publication Type:Journal Article
Keywords: Poor ovarian response; Luteal phase stimulation; Frozen embryo transfer; Double stimulation
From: Chinese Journal of Reproduction and Contraception 2021;41(9):839-842
CountryChina
Language:Chinese
Abstract: Poor ovarian response (POR) is a reproductive endocrinology disease that seriously affects the number of oocytes retrieved and reduces the success rate of in vitro fertilization (IVF). The double stimulation protocol utilizes the principle of ovarian stimulation in both the follicular and luteal phase. By retrieving oocytes within one menstrual cycle, more oocytes can be obtained in a fairly short period of time. Therefore, to further explore this new ovarian stimulation protocol may help to provide better treatment strategies for POR patients. This paper reviews the definition of POR, the mechanism and developments of double stimulation, and its application in POR patients.