Clinical efficacy of photodynamic therapy combined with subgingival glycine powder air polishing for the management of re-sidual periodontal pocket of stage Ⅲ periodontitis
10.13591/j.cnki.kqyx.2025.10.007
- VernacularTitle:光动力疗法联合甘氨酸龈下喷砂对治疗Ⅲ期牙周炎残留牙周袋的临床疗效研究
- Author:
Yue XU
1
;
Jiaojiao XIA
1
;
Yulian CHEN
1
;
Qiang CHEN
1
Author Information
1. 苏州口腔医院牙周病科,江苏苏州(215000)
- Publication Type:Journal Article
- Keywords:
photodynamic therapy;
subgingival glycine powder air polishing;
stage Ⅲ periodontitis;
residual periodontal pocket
- From:
STOMATOLOGY
2025;45(10):760-764
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and the impact on the periodontal microenvironment of photodynamic therapy(PDT)combined with subgingival glycine powder air polishing(SubGPAP)for patients with stage Ⅲ periodontitis on residual periodontal pockets.Methods Forty patients who visited the Department of Periodontology at our hospital with stage Ⅲ periodontitis were selected.After 4-6 weeks of initial treatment,the residual periodontal pockets of＞4 mm depth with bleeding on probing,or ≥6 mm depth were randomly assigned in a split-mouth design,to receive subgingival scaling and root planning(SRP)(control group)or PDT+SubGPAP+SRP(test group).Indicators including probing depth(PD),clinical attachment loss(CAL),bleeding index(BI),plaque index(PLI),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-1β(IL-1β)at baseline,6 weeks and 3 months after treatment were measured and compared.Results The clinical indicators showed significant reductions in both groups at 6 weeks and 3 months compared with those at baseline(P＜0.05).The TNF-α in test group showed no significant differ-ence at 3 months compared with 6 weeks(P＞0.05),while the other indicators in both groups showed significant reductions at 3 months compared with those at 6 weeks(P＜0.05).The PD,CAL,BI,TNF-α,IL-6 and IL-1β in test group showed a significant reduction than those in the control group at 6 weeks and 3 months(P＜0.05).The PLI in test group showed a significant reduction at 6 weeks(P＜0.05).Conclusion PDT combined with SubGPAP assisted SRP for patients with stage Ⅲ periodontitis on residual periodontal pockets is conducive to enhancing the clinical efficacy and improving the microenvironment.
