Design and Verification of Implantable Central Venous Dialysis Port
10.16156/j.1004-7220.2025.05.024
- VernacularTitle:植入式中心静脉透析港的设计与验证
- Author:
Yangzhi LIU
1
;
Qingjing LIN
1
;
Qinxian GAO
1
;
Chengli SONG
1
Author Information
1. 上海理工大学健康科学与工程学院,上海 200093
- Publication Type:Journal Article
- Keywords:
hemodialysis;
implantable venous access port;
central venous catheter;
finite element analysis;
fluid experiment
- From:
Journal of Medical Biomechanics
2025;40(5):1265-1271
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design and verify an implantable dialysis port that enables the central venous catheter to no longer be placed on the body surface,and to study the effect of the central venous catheter's structural design on its performance.Methods The feasibility of the dialysis port was verified by flow and pressure experiments.Four representative catheter structures were analyzed by finite element method.The recirculation rate,flow rate-pressure ratio and proportion of indwelling particles were recorded,and performance differences were analyzed.An experimental platform was built to verify the simulation conclusion,and the fluid flow direction of the arteriovenous cavity was quantified by the salinity measurement method.Results The dialysis port could reach the flow requirement of 300 mL/min under the 45 kPa pressure.The recirculation rate of the measured central venous catheter was between 10.7％and 23.5％,and the residual value of heparin was between 2.3％and 2.8％.The performance of the catheter with bundle mouth,positive position and side hole structure was better.Conclusions The implantable dialysis port can potentially cooperate with central venous catheters to establish a new vascular access approach.The structure of the central venous catheter should adopt the design of bundle mouth,positive position and side hole,which has better recirculation rate and heparin locking performance with low flow rate-pressure ratio.This study provides a theoretical and experimental basis for structural design and clinical selection of the central venous catheter.
