Establishment of Reference Intervals for Venous Whole Blood Red Cell and Related Parameters in Healthy Children Preschool Stage 3～6 Years in Panzhihua,Sichuan Province
10.3969/j.issn.1671-7414.2025.05.032
- VernacularTitle:四川省攀枝花地区学龄前期3～6岁健康儿童静脉全血红细胞及相关参数参考区间的建立
- Author:
Jiaming LI
1
;
Jiaxin LI
;
Xinfei LI
;
Wenxiang YANG
;
Tingting LI
;
Fulin HUANG
Author Information
1. 攀钢集团总医院检验科,四川 攀枝花 617000
- Publication Type:Journal Article
- Keywords:
reference range;
health children;
vein whole blood;
red blood cells;
red cell volume distribution width
- From:
Journal of Modern Laboratory Medicine
2025;40(5):167-171
- CountryChina
- Language:Chinese
-
Abstract:
Objective The reference interval of venous whole blood red cells and related parameters of healthy children preschool stage 3 to 6 years in Panzhihua was established to provide practical experimental basis for pediatric clinical diagnosis and treatment.Methods From January to July 2023,1 467 eligible healthy children from 3 to 6 years old for physical examination were collected as study subjects,including 762 boys and 705 girls.Red blood cell(RBC),hemoglobin(Hb),hematocrit(HCT),mean red blood cell volume(MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC)and red cell volume distribution width(RDW)were measured by Sysmex XN-1000 automatic blood analyzer.According to sex and age groups,the differences of the above indexes between different gender and age groups were compared,and the reference interval of venous whole blood red cells and related parameters of healthy children aged 3 to 6 years old in Panzhihua was established.At the same time,25 samples(including 13 boys and 12 girls)were selected to verify the newly established reference interval.Results HCT and RDW-SD reference intervals between boys and girls preschool stage 3～6 in the Panzhihua area,and the differences were not statistically significant(U=0.000,0.795,all P>0.05).The reference intervals for RBC,MCV,MCH and RDW-CV show statistically significant differences between boys and girls(U=2.829～5.753,all P＜0.05).There were gender and age differences in the reference intervals of Hb and MCHC(U=2.599,4.368,all P＜0.01).In the 3～6 years,the basal levels of RBC,HGB and HCT tended to increase gradually with age,while the overall base levels of RBC,HGB,MCHC,and RDW-CV in boys were higher than those in girls.And there were different degrees of difference with the reference range of industry standards.Also verify through the new reference interval.Conclusion With differences in RBC and related reference intervals of preschool stage children in different regions,it is necessary to establish a reference interval suitable for special population in Panzhihua.
