Mechanisms of Selenoproteins in Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2025.01.009
- VernacularTitle:硒蛋白在炎症性肠病中的作用机制
- Author:
Xiaoyue FENG
1
;
Ying KANG
;
Kang JIANG
;
Chunyan CHEN
;
Weijun XU
;
Fangyu WANG
Author Information
1. 解放军东部战区总医院消化内科(210002);南京医科大学金陵临床医学院
- Publication Type:Journal Article
- Keywords:
Selenium;
Selenoproteins;
Inflammatory Bowel Disease;
Colitis-Associated Cancer;
Therapy
- From:
Chinese Journal of Gastroenterology
2025;30(1):47-51
- CountryChina
- Language:Chinese
-
Abstract:
Selenium is an essential trace element for human body.The primary functional form of selenium in the organism is selenoproteins(Sep),which plays a crucial role in maintaining normal physiological functions,influencing immune responses,and is also implicated in tumorigenesis and related metabolic disorders.Recent studies have shown that Sep is involved in the pathophysiological process of inflammatory bowel disease(IBD).This article reviewed the mechanisms of Sep in IBD,aiming to explore the pathogenic mechanisms of IBD and provide insights for the diagnosis and treatment of the disease.
