Impact of Endoscopic Timing on Prognosis of Patients With Peptic Ulcer Bleeding
10.3969/j.issn.1008-7125.2025.01.008
- VernacularTitle:内镜检查时机对消化性溃疡出血患者预后的影响
- Author:
Huiqin HU
1
;
Bingsheng LI
1
Author Information
1. 广东省惠州市第一人民医院消化内科(516003)
- Publication Type:Journal Article
- Keywords:
Peptic Ulcer Hemorrhage;
Endoscopic Timing;
Rebleeding;
Prognosis
- From:
Chinese Journal of Gastroenterology
2025;30(1):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Background:Peptic ulcer bleeding(PUB)represents the leading etiology of acute upper gastrointestinal bleeding.Currently,endoscopy within 24 hours after admission is recommended for patients with acute upper gastrointestinal bleeding,but the optimal timing remains uncertain.Aims:To investigate the impact of endoscopic timing on the prognosis of patients with PUB.Methods:A retrospective analysis was conducted on PUB patients presenting with gastrointestinal bleeding symptoms who underwent gastroscopy within 24 hours after admission at Huizhou First Hospital from January 2019 to December 2022.According to the endoscopic timing after admission,patients were divided into urgent endoscopy group(≤8 hours after admission)and early endoscopy group(8-24 hours after admission).The 30-day rebleeding rate,rate of adverse in-hospital outcomes,length of hospital stay,hospitalization cost,and blood transfusion rate were compared between the two groups.Results:A total of 608 PUB patients were enrolled.The 30-day rebleeding rate was 6.6%.No significant differences in 30-day rebleeding rate,rate of adverse in-hospital outcomes,length of hospital stay and blood transfusion rate were found between the urgent endoscopy group and early endoscopy group(all P>0.05).However,hospitalization cost was significantly higher in urgent endoscopy group(P=0.002).In 376 patients with high-risk ulcer,the 30-day rebleeding rate was 10.4%.High-risk ulcer patients receiving urgent endoscopy demonstrated significantly lower 30-day rebleeding rate(7.3%vs.13.7%,P=0.042)and rate of adverse in-hospital outcomes(4.1%vs.10.4%,P=0.019),while there were no significant differences in length of hospital stay,hospitalization cost,and blood transfusion rate between the two subgroups(all P>0.05).Conclusions:Urgent endoscopy within 8 hours after admission does not reduce the 30-day rebleeding rate and rate of adverse in-hospital outcomes in patients with PUB.However,patients with high-risk ulcer may benefit from urgent endoscopy within 8 hours after admission.
