Development status for cryopreservation and transplantation of human ovarian tissue
10.3760/cma.j.cn101441-20190806-00344
- VernacularTitle:人类卵巢组织冷冻保存与移植技术发展现状
- Author:
Cancan ZHU
1
;
Zhaoqing LIU
1
;
Nianmin QI
1
Author Information
1. 上海坤爱生物科技股份有限公司 201318
- Publication Type:Journal Article
- Keywords:
Ovarian tissue cryopreservation;
Fertility;
Oocyte cryopreservation;
Embryo cryopreservation
- From:
Chinese Journal of Reproduction and Contraception
2020;40(9):773-777
- CountryChina
- Language:Chinese
-
Abstract:
The cancer patients may experience ovarian dysfunction and lose their fertility after radiotherapy or chemotherapy. Therefore, the oncologists face problems of how to protect reproductive function and improve their life quality of young female patients. Ovarian tissue cryopreservation and transplantation (OTCT) could restore the female reproductive endocrine and is one of the main methods for fertility preservation. This method provides a new way for patients who are not suitable for fertility preservation by oocyte cryopreservation and embryo cryopreservation. In recent years, there are many heathy births by OTCT. But, this method also has deficiencies, such as ischemic atresia after transplantation before rebuilding blood supply and risk of reintroducing the malignant cells after retransplantation. This paper reviews the development of OTCT.
