Application of bedside critical ultrasound-guided volume management in the maintenance of acute kidney injury donors
10.12464/j.issn.1674-7445.2025069
- VernacularTitle:床旁重症超声引导的容量管理在急性肾损伤供者维护的应用
- Author:
Xiaomian LIU
1
;
Feixiong PANG
1
;
Guo RAN
1
;
Jiazhi LI
1
;
Yanhua LAI
1
Author Information
1. 530021 南宁,广西壮族自治区人民医院移植中心
- Publication Type:Journal Article
- Keywords:
Bedside critical ultrasound;
Volume management;
Acute kidney injury;
Kidney transplantation;
End-stage kidney disease;
Donor kidney function;
Delayed graft function;
Serum creatinine
- From:
Organ Transplantation
2025;16(5):771-777
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application effect of bedside critical ultrasound in volume management of acute kidney injury(AKI)donors.Methods Clinical data of 56 AKI donors and 106 recipients from the Transplantation Center of People's Hospital of Guangxi Zhuang Autonomous Region from October 1,2020 to May 31,2022 were collected.They were divided into the critical ultrasound group(34 donors,66 recipients)and the traditional central venous pressure(CVP)group(22 donors,40 recipients)according to the volume management methods.The AKI stage and recovery time,renal function indicators(serum creatinine(Scr),cystatin C,estimated glomerular filtration rate),donor Remuzzi score,cold ischemia time,biventricular inotrope usage rate and time,delayed graft function(DGF)incidence and recovery time,and renal function indicators at 6 and 12 months after surgery were compared and analyzed between the two groups.Results There were no statistically significant differences in gender,age,body weight,AKI stage,pre-acquisition renal function indicators,biventricular inotrope usage rate,renal function indicators at 6 and 12 months after surgery,DGF recovery time,donor Remuzzi score and cold ischemia time of the donors and recipients between two groups(all P>0.05).The AKI recovery time,continuous renal replacement therapy rate and biventricular inotrope usage time of donors in the critical ultrasound group were shorter or lower than those in the traditional CVP group(all P<0.05).The incidence of DGF in recipients of the critical ultrasound group was lower than that of the traditional CVP group(P<0.05).Subgroup analysis showed that there was no statistically significant difference in Scr at 6 and 12 months after surgery in recipients of the critical ultrasound group(P>0.05),while the Scr at 12 months after surgery was higher than that at 6 months in recipients of the traditional CVP group(P<0.05).Conclusions AKI kidneys may be used for kidney transplantation after active maintenance.Bedside critical ultrasound has unique advantages in volume management of AKI donors and may improve the function of AKI kidneys to a certain extent.
