Impact of bilateral salpingectomy on ovarian response in controlled ovarian stimulation cycle
10.3760/cma.j.cn101441-20191119-00516
- VernacularTitle:双侧输卵管切除术对控制性卵巢刺激周期卵巢反应的影响
- Author:
Jiayu XU
1
;
Yanrong CHEN
1
;
Ningning PAN
1
;
Yan YANG
1
;
Shuo YANG
1
;
Rong LI
1
;
Caihong MA
1
Author Information
1. 北京大学第三医院生殖医学中心 100191
- Publication Type:Journal Article
- Keywords:
Salpingectomy;
Hydrosalpinx;
Controlled ovarian stimulation;
Ovarian reserve;
Fertilization in vitro;
Embryo transfer
- From:
Chinese Journal of Reproduction and Contraception
2020;40(7):535-539
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of bilateral salpingectomy on ovarian response in controlled ovarian stimulation (COS) cycles of women with hydrosalpinx.Methods:Women with hydrosalpinx who underwent bilateral salpingectomy and COS before and after salpingectomy within 1 year between Jan. 2010 and Nov. 2017 in Peking University Third Hospital were included in study group. Women with male factor infertility who received COS at the same period and matched with age according to the ratio of 1:2 were included in control group. A retrospective analysis of ovarian reserve and COS before and after salpingectomy in study group and between the two groups was performed.Results:A total of 132 patients were recruited in study group and 264 patients in control group. Compared between after and before salpingectomy in study group, there were no significant diffrences in basal serum follicle-stimulating hormorne (FSH) level [(6.76±2.15) IU/L vs. (6.62±2.03) IU/L, P=0.589], estradiol level [(160.77±66.20) pmol/L vs. (161.58±66.42) pmol/L, P=0.922], antral follicle count (AFC) (9.36±4.28 vs. 10.27±5.01, P=0.135), the number of oocytes retrieved (11.18±7.43 vs. 11.68±6.20, P=0.278) and viable embryos (4.82±4.14 vs. 5.14±3.55, P=0.166). Between study group and control group, there were no differences in age, basal FSH, estradiol level, AFC, duration and dosage of gonadotropin (Gn) used, number of oocytes collected and transferable embryos ( P>0.05). Conclusion:Careful bilateral salpingectomy does not decrease ovarian reserve and response in COS cycles of women with normal ovarian reserve.