Analysis of Influencing factors on the therapeutic effect of endoscopic retrograde cholangiopancreatography stent implantation for Malignant obstructive jaundice
10.3969/j.issn.1005-6483.20240703
- VernacularTitle:恶性梗阻性黄疸经内镜逆行性胰胆管造影支架置入术疗效影响因素分析
- Author:
Hongxu LI
1
;
Jinzhi SONG
1
;
Yang CHEN
1
;
Jianbo XIAO
1
;
Shoujun WANG
1
Author Information
1. 621100 四川绵阳,川北医学院附属三台医院肝胆乳腺科
- Publication Type:Journal Article
- Keywords:
malignant obstructive jaundice;
endoscopic retrograde cholangiopancreatography;
stand;
clinical effect
- From:
Journal of Clinical Surgery
2025;33(8):856-859
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of ERCP stent implantation for patients with malignant obstructive jaundice.Methods 130 patients with malignant obstructive jaundice who received ERCP stent implantation in our hospital from January 2017 to January 2024 were retrospectively included,and grouped according to the jaundice control effect 4 weeks after surgery.Univariate and multivariate analysis of the efficacy of ERCP stent placement in malignant obstructive jaundice after 4 weeks.Construction of a predictive model for the efficacy of ERCP stent placement in malignant obstructive jaundice after 4 weeks and clinical efficacy analysis.Results There were 64 cases for jaundice resolved in 4 weeks after surgery among all 130 patients with the regression rate for 49.23％.The results of univariate analysis showed that the type of biliary obstruction,stent type,and preoperative Child Pugh grading may all be related to the efficacy of ERCP stent placement in malignant obstructive jaundice after 4 weeks(P＜0.05).The results of Logistic multivariate analysis showed that the type of biliary obstruction,stent type,and preoperative Child Pugh grade were all independent influencing factors on the efficacy of ERCP stent placement for malignant obstructive jaundice at 4 weeks(P＜0.05).Using the independent influencing factors and P-value prediction probability of Logistic regression model to predict the prognosis of patients,the ROC curve was used,with areas under the curve of 0.713,0.823,0.907,and 0.971,respectively.Conclusion The clinical effects of ERCP stent implantation in malignant obstructive jaundice was closely related to the type of biliary obstruction,stent type and preoperative Child-Pugh grade.The data model constructed using the above three factors has shown good performance in predicting the prognosis of patients.
