Predictive Value of Hemoglobin to Serum Creatinine Ratio for 3-year All-cause Mortality After Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
10.3969/j.issn.1000-3614.2025.09.010
- VernacularTitle:血红蛋白与血肌酐比值对ST段抬高型心肌梗死患者经皮冠状动脉介入治疗术后3年全因死亡的预测价值
- Author:
Meimei LIU
1
;
Pengyu QIAO
;
Jiayao XIANG
;
Sihe LIU
;
Yuxia MA
;
Lin HAN
;
Fanghong YAN
Author Information
1. 兰州大学循证护理中心 兰州大学护理学院,兰州 730000;甘肃省人民医院 护理部,兰州 730000
- Publication Type:Journal Article
- Keywords:
ST-segment elevation myocardial infarction;
percutaneous coronary intervention;
all-cause mortality;
hemoglobin;
serum creatinine;
hemoglobin to serum creatinine ratio
- From:
Chinese Circulation Journal
2025;40(9):904-911
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To investigate the predictive value of the hemoglobin to serum creatinine ratio(Hb/SCr)for all-cause mortality within 3 years after percutaneous coronary intervention(PCI)in patients with ST-segment elevation myocardial infarction(STEMI).Methods:A total of 687 STEMI patients who successfully underwent the first PCI at the Department of Cardiology,Gansu Provincial People's Hospital,from June 2016 to June 2020 were retrospectively enrolled.Patients were divided into survival and non-survival groups according to their vital status at 3 years post-PCI.Cox regression analysis was performed to identify predictive factors of all-cause mortality.Receiver operating characteristic(ROC)curves were constructed to evaluate the predictive value of Hb/SCr for all-cause mortality,and Kaplan-Meier survival curves were used to compare cumulative survival rates between subgroups stratified by Hb/SCr levels.Results:The median follow-up duration was 37(25,50)months.Among the 663 patients(96.51%)with complete follow-up data,41 cases(6.18%)experiencing all-cause death.Multivariable Cox regression analysis revealed that age(HR=1.086,95%CI:1.037-1.137,P=0.000),body mass index(HR=1.195,95%CI:1.128-1.266,P=0.000),fasting blood glucose(HR=1.069,95%CI:1.007-1.135,P=0.030),fibrinogen(HR=1.418,95%CI:1.120-1.795,P=0.004),TIMI flow grade 1(HR=4.968,95%CI:1.194-20.667,P=0.028),TIMI flow grade 2(HR=3.861,95%CI:1.336-11.156,P=0.013),and Hb/SCr(HR=0.858,95%CI:0.766-0.961,P=0.008)were the independent predictors of all-cause mortality.ROC curve analysis demonstrated that the area under the curve(AUC)of Hb/SCr was 0.721(95%CI:0.645-0.798)for predicting all-cause mortality,with a sensitivity of 65.9%and specificity of 71.2%,at the optimal cut-offvalue of 16.627.Kaplan-Meier analysis showed that patients with Hb/SCr<16.627 had significantly lower survival rates than those with Hb/SCr≥16.627(log-rank P=0.000).Conclusions:Hb/SCr is an independent predictor of 3-year all-cause mortality in STEMI patients after PCI and this indicator could be used as risk stratification parameter and patients with lower Hb/SCr might benefit comprehensive post-PCI management to improve their outcome.
