Efficacy of anticoagulation treatment alone and combining mechanical thrombectomy for cerebral venous sinus thrombosis
10.13929/j.issn.1672-8475.2025.08.001
- VernacularTitle:单一抗凝治疗与其联合机械取栓用于颅内静脉窦血栓效果
- Author:
Lei YAN
1
;
Zhen XU
1
;
Wenying BAO
1
;
Yingge XU
1
;
Song ZHANG
1
;
Ming ZHU
1
;
Yinyin WU
1
;
Shaofeng SHUI
1
Author Information
1. 郑州大学第一附属医院放射介入科,河南 郑州 450052
- Publication Type:Journal Article
- Keywords:
sinus thrombosis,intracranial;
treatment outcome;
thrombectomy;
anticoagulation treatment
- From:
Chinese Journal of Interventional Imaging and Therapy
2025;22(8):497-501
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of anticoagulation treatment(AT)alone and combining mechanical thrombectomy(MT)for cerebral venous sinus thrombosis(CVST).Methods Totally 150 patients with CVST were collected,including 90 underwent only AT(AT group)and 60 underwent MT+AT(combined group).The rate of venous sinus recanalization at discharge,the prognosis at discharge and 6,12 months after discharge(modified Rankin scale[mRS]score of 0 to 2 was considered as good prognosis)were compared between groups,and relative complications were recorded.Results At discharge,the rate of complete and partial recanalization of venous sinuses in combined group were both higher than that in AT group(both P＜0.001).No significant difference of the rate of good prognosis at discharge was found between groups(P=0.191),while 6 and 12 months after discharge,the rate of good prognosis in combined group were both higher than that in AT group(P=0.046,0.028).During the treatment and follow-up period,no significant difference of the incidence of complications was found between groups(5.00%[3/60]vs.11.11%[10/90],P=0.245).Conclusion Compared with AT alone,AT combining with MT could improve revascularization rate and prognosis of CVST without increasing the risk of complications.
