Research Progress and Evaluation of Animal Models for the Study of Obesity and Its Associated Complications
- VernacularTitle:肥胖症及其并发症动物模型的研究进展与评价
- Author:
Ziyuan SONG
1
;
Libin ZHAN
;
Ningzi ZANG
;
Tianshu GAO
;
Chengjun GONG
;
Rumeng MEI
;
Xuelian LI
;
Pin LI
Author Information
- Publication Type:Journal Article
- Keywords: Obesity disease; Obesity complications; Animal model; Molding method
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(9):2687-2698
- CountryChina
- Language:Chinese
- Abstract: With the development of society,the incidence of obesity has increased year by year in recent years,which has seriously jeopardized public health and safety,and has been a hot spot in the field of endocrine research.At the same time,obesity is also an important cause of a variety of metabolic diseases,such as metabolic syndrome,pre-diabetes,hypertension and polycystic ovary syndrome and other diseases,but the etiology and mechanism of obesity have not been completely clear,and basic research on obesity of traditional Chinese and western medicine still needs to be widely carried out.In this paper,animal models of obesity and its complications will be comprehensively summarized,and the model principles will be elaborated in combination with TCM syndromes and western medicine mechanisms,and evaluate their merits and demerits,so as to provide references for the selection of reasonable animal models for relevant experimental studies of obesity.
