Efficacy of enteral nutrition in preventing bone marrow suppression in patients with nasopharyngeal carcinoma undergoing concurrent radiotherapy and chemotherapy
10.16753/j.cnki.1008-2344.2025.05.008
- VernacularTitle:肠内营养对预防鼻咽癌同期放化疗患者骨髓抑制的疗效观察
- Author:
Jinhua LIAO
1
;
Lipeng LIU
;
Jinwei LI
;
Xiaoyun LIU
;
Lu ZHANG
Author Information
1. 赣州市肿瘤医院临床营养科,江西 赣州 341000
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma;
concurrent radiotherapy and chemotherapy;
enteral nutrition;
bone marrow suppression
- From:
Journal of Shenyang Medical College
2025;27(5):492-496,513
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of enteral nutrition in preventing bone marrow suppression in patients with nasopharyngeal carcinoma undergoing concurrent radiotherapy and chemotherapy.Methods:The clinical data of 150 nasopharyngeal carcinoma patients undergoing concurrent radiotherapy and chemotherapy treatment in our hospital from Sep 2022 to Sep 2024 were analyzed.They were divided into the conventional group(74 cases)and the enteral nutrition group(76 cases)according to different nutritional intervention plans.The conventional group received conventional nutritional therapy,while the enteral nutrition group received enteral nutrition therapy.The occurrence of bone marrow suppression,blood routine indicators,nutritional status indicators were compared,and quality of life was evaluated with cancer patient quality of life measurement scale(EORTC-QLQ-C30)and compared.Results:The total incidence of bone marrow suppression in the enteral nutrition group was lower than that in the conventional group(P＜0.05),and the degree of bone marrow suppression was milder than that in the conventional group(P＜0.05).At the end of treatment,the enteral nutrition group had higher levels of hemoglobin,granulocytes count,red blood cells count,white blood cells count,platelets count,body mass index,upper arm circumference,waist circumference,and scores of each functional domain of EORTC-QLQ-C30 compared to the conventional group(P＜0.05).Conclusion:Enteral nutrition therapy for nasopharyngeal carcinoma patients undergoing concurrent radiotherapy and chemotherapy can prevent bone marrow suppression,improve blood routine indicators and nutritional status,and enhance quality of life.
