Advances in diagnosis and treatment of colorectal cancer with bone marrow metastasis
10.3760/cma.j.cn115610-20250331-00127
- VernacularTitle:结直肠癌骨髓转移的诊断与治疗进展
- Author:
Mingya JIN
1
;
Jun QIN
;
Xinwen WEI
;
Ying HAN
;
Ming ZHONG
Author Information
1. 宁波市杭州湾医院（上海交通大学医学院附属仁济医院宁波医院)普通外科，宁波 315336
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Bone marrow;
Metastasis;
Disseminated intravas-cular coagulation;
Chemotherapy
- From:
Chinese Journal of Digestive Surgery
2025;24(6):777-780
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the common malignant tumor in China. However, cases of colorectal cancer with synchronous bone marrow metastasis are extremely rare in clinical practice, and there are few reports on its treatment worldwide. Due to the destructed hematopoietic function caused by tumor cells occupying the bone marrow, the efficacy of chemotherapy, targeted therapy and immunotherapy is very poor. As a result, colorectal cancer with bone marrow metastasis has a very high mortality and very short survival, resulting in a very poor prognosis. The authors review the epidemiology, etiology, pathogenesis, clinical features, diagnosis methods, treatment options and prognosis of this disease.
