Pathogenesis of Ulcerative Colitis Accompanied by Anxiety and Depression and Advances in Traditional Chinese Medicine Treatment
10.14148/j.issn.1672-0482.2025.1312
- VernacularTitle:溃疡性结肠炎伴焦虑抑郁的机制研究及中医药治疗进展
- Author:
Yuting WANG
1
;
Lei ZHU
1
Author Information
1. 南京中医药大学附属医院,江苏 南京 210029
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
anxiety and depression;
pathogenesis;
traditional Chinese medicine;
liver depression and spleen de-ficiency
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(10):1312-1319
- CountryChina
- Language:Chinese
-
Abstract:
Prevalence of ulcerative colitis(UC)accompanied by anxiety and depression continues to rise,with mechanisms closely linked to brain-gut-microbiota axis dysregulation and inflammatory responses.Traditional Chinese medicine(TCM)theory posits that the core pathogenesis lies in"liver depression and spleen deficiency".TCM treatment demonstrates potential in alleviating UC with anx-iety and depression through its characteristic advantages of"holistic regulation and mind-body co-treatment".This article elucidates the pathogenesis from both Western medicine and TCM perspectives and reviews research progress on TCM interventions,aiming to pro-vide a theoretical basis for precise UC diagnosis/treatment and multidisciplinary intervention strategies.