Research progress of regulated cell death in inflammatory bowel disease
10.3969/j.issn.1000-484X.2025.10.035
- VernacularTitle:调节性细胞死亡在炎症性肠病中的研究进展
- Author:
Mengfan TANG
1
;
Yu FU
1
Author Information
1. 华中科技大学同济医学院附属协和医院消化内科,武汉 430022
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Regulated cell death;
Intestinal inflammation
- From:
Chinese Journal of Immunology
2025;41(10):2514-2520
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease(IBD)is a group of chronic and recurrent intestinal inflammatory diseases,and the pathogenesis of IBD is complex,it is currently believed that IBD is mainly caused by the interaction of multiple factors,such as genetic susceptibility,host immune dysfunction,intestinal flora imbalance,impaired intestinal mucosal barrier integrity and the environment.Regulated cell death(RCD)mediated by signaling pathways and clear mechanisms of action,plays a crucial role in maintaining homeostasis and the occurrence and progression of a variety of diseases,including IBD.This article reviews the research progress of RCD in IBD.
