Development history and research progress of polymeric heart valves
10.3969/j.issn.1004-8812.2025.09.006
- VernacularTitle:聚合物瓣膜的发展历史及研究进展
- Author:
Lei LU
1
;
Wen-zhi PAN
Author Information
1. 上海理工大学东方泛血管器械创新学院,上海 200093
- Publication Type:Journal Article
- Keywords:
Polymeric heart valves;
Valve replacement;
Heart valve;
Durability;
Hemodynamics
- From:
Chinese Journal of Interventional Cardiology
2025;33(9):523-531
- CountryChina
- Language:Chinese
-
Abstract:
Valvular heart disease(VHD)is a prevalent structural cardiac disorder,and prosthetic valve replacement remains the most effective treatment for patients with severe VHD.However,existing prosthetic valves have certain limitations:mechanical valves require lifelong anticoagulation therapy,while bioprosthetic valves have limited durability,particularly posing a risk of reoperation in younger patients.Therefore,improving the performance and longevity of artificial valves has become a key research focus.In recent years,breakthroughs in material science have driven the rapid development of polymeric materials,offering more options for heart valve applications.Compared with bioprosthetic valves,polymeric valves are thinner,more durable,and exhibit better blood compatibility,showing great clinical potential.Currently,polymeric valves represented by the SIKELIA system and Tria surgical valve are gradually entering clinical practice,with mid-and short-term results demonstrating their effectiveness and safety.This review summarizes the materials,fabrication techniques,and current global status of polymeric heart valves,aiming to provide insights for further research and clinical application in this field.
