Research progress on the association between non-thrombotic cerebral venous outflow disorder and cognitive impairment
10.3969/j.issn.1004-1648.2025.05.017
- VernacularTitle:非血栓性脑静脉回流障碍与认知障碍间关联的研究进展
- Author:
Xiao XU
1
;
Yefei WU
1
;
Hongwei SHI
1
Author Information
1. 210006 南京医科大学附属南京医院(南京市第一医院)麻醉疼痛与围术期医学科
- Publication Type:Journal Article
- Keywords:
cerebral venous reflux disorder;
venous stenosis;
cognitive impairment;
neuroinflammation
- From:
Journal of Clinical Neurology
2025;38(5):381-385
- CountryChina
- Language:Chinese
-
Abstract:
Cerebrovascular diseases such as cerebral embolism and atherosclerosis can lead to ischemic or hemorrhagic brain injury,and clinically,cognitive impairment has been observed in certain patients.Many previous studies have focused on cerebral hypoperfusion caused by arterial system abnormalities and explored the association between it and cognitive impairment.As an important vascular component for maintaining brain functional homeostasis,the cerebral venous system may also play a role in the development of cognitive impairment when there is venous reflux disorder.This paper explores the clinical association between non-thrombotic cerebral venous reflux disorder and cognitive impairment,and proposes that venous system abnormalities affect cognitive function through mechanisms such as neuroinflammation and metabolic disorders,suggesting that cerebral venous reflux disorder may be a potential independent cause of cognitive impairment.
